Addison's disease is
a rare endocrine, or hormonal disorder that affects about 1 in 100,000
people. It occurs in all age groups and affects men and women equally.
The disease is characterized by weight loss, muscle weakness, fatigue,
low blood pressure, and sometimes darkening of the skin in both
exposed and nonexposed parts of the body. Addison's is a severe
or total deficiency of the hormones made in the adrenal cortex,
caused by a destruction of the adrenal cortex. There are normally
two adrenal glands, located above each kidney. The adrenal glands
are really two endocrine, ductless or hormone producing, glands
in one. The inner part of the adrenal, called the medulla, produces
epinephrine also called adrenaline, which is produced at times of
stress and helps the body respond to "fight or flight"
situations by raising the pulse rate, adjusting blood flow, and
raising blood sugar. However, the absence of the adrenal medulla
and epinephrine does not cause disease. In contrast, the outer portion
of the adrenal, the cortex, is more critical. The adrenal cortex
makes two important steroid hormones, cortisol and aldosterone.
Cortisol mobilizes nutrients, modifies the body's response to inflammation,
stimulates the liver to raise the blood sugar, and also helps to
control the amount of water in the body. Aldosterone regulates salt
and water levels which affects blood volume and blood pressure.
Cortisol production is regulated by another hormone, adrenocorticotrophic
hormone (ACTH), made in the pituitary gland which is located just
below the brain. Classical Addison's Disease results from a loss
of both cortisol and aldosterone secretion due to the near total
or total destruction of both adrenal glands. This condition is also
called primary adrenal insufficiency. If ACTH is deficient, there
will not be enough cortisol produced, although aldosterone may remain
adequate. This is secondary adrenal insufficiency, which is distinctly
different, but similar to Addison's Disease, since both include
a loss of cortisol secretion. From http://www.medhelp.org/nadf/nadf3.htm.
Accommodation ideas for
individuals with Addison's Disease may include:
Managing Fatigue: An individual with Addison's Disease may
benefit from a flexible work schedule, liberal use of leave time,
being allowed to work from home, a reduction or elimination of
physical exertion and workplace stress, scheduled rest breaks
away from the workstation, and ergonomic
workstation design.
Controlling Weight: Because of salt loss, a craving for salty
foods is common. Easy access to snacks and a refrigerator may
help.
Working in a Cold Environment: Specially designed clothing,
individual space heaters, and controlled thermostats can reduce
the effects of working in a cold environment. Allowing work from
home during extremely hot or cold weather, maintenance of the
ventilation system, and redirecting air conditioning and heating
vents may also help.
Difficulty Standing
and Walking due to Blood Pressure Loss: A wheelchair
or scooter
may accommodate these limitations when moving around a workplace.
Stand/lean
stools and adjustable
workstations also help individuals convert standing areas
to sitting workstations.
Low Vision: An
individual with a Addison's may have low vision. For information
on accommodations for individuals with vision impairments, visit
SOAR's Accommodations for Vision
Impairments or JAN's general publication on Work-site
Accommodation Ideas for Individuals with Vision Impairments.
Managing Depression:
Developing workplace strategies to deal with work problems before
they arise, providing sensitivity training to coworkers, allowing
telephone calls during work hours to doctors and others for support,
and easy access to information on counseling and employee assistance
programs are beneficial.
Organizations